Carl's Roost:
MRI Artifact Gallery
This is a collection of MRI images
demonstrating some common and not so-common
artifacts. Many of the artifacts occur to some
extent in more than one image, there are multiple
names for some types of artifacts, and some images
illustrate multiple problems. The following list is
provided as an index:
Raw data (interferograms) are also
displayable in some cases. These are typically just
the real part of the complex raw data, and have been
scaled to emphasize the interesting
details. Therefore, they cannot be successfully
transformed to reproduce the displayed images.
In some cases, the original data file may be
available for downloading and further
investigation. If this file is available, it is in the
Surrey Medical Imaging Systems (SMIS) ".MRD" format.
All such files should be downloaded or saved to disk
as "raw", "binary" or "source", depending on your
browser.
Note: The appearance of the images will depend
strongly upon your browser, and monitor or printer
settings. Some of the artifacts are subtle enough that
a poor display setup may mask them completely. You
can download the image and view it off line with
better software, if necessary.
Acknowledgements: This collection was
started during a Biophysics 404 class at the
University of Illinois in Fall 1994. Thanks to Jill
Hanson for compiling the original list. This work is
supported by the U.S. National Institutes of Health,
Center for Research Resources, and the University of
Illinois.
Experimental
details are at the end.
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std001.sur - Reference
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This image is as close to "ideal" as we could
get. Compare each of the other images to this. Note
that the position of the phantom does change in some
of the images.
Interferogram and raw data file
available.
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arc001.gif - Data Spike
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drop001.gif - Dropout
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These images demonstrate intermittent corruption of
the data, typically by electrical problems. They have
been artificially generated by using viewit
to modify the raw data from the reference image before
transforming it. On the left, a few data points have
been modified, as might happen if an electrical
transient (such as a static discharge, sometimes
called an "arc") occured during the digitization of
one echo. Note the elevated background level. The
venetian blind pattern becomes a crosshatch with two
arcs, and with multiple arcs, may be indistinguishable
from random noise. Note that a transmitter
arc looks different, since it affects the MR
magnetization directly, and does not occur during
digitization. See the
instability
example for what might
appear in that case. Interferogram here.
You'll have to look very closely to see the spike, in
the upper left quadrant.
On the right, some part of each of three rows of
the data has been set to zero, as might happen if a
computer problem caused loss of data, or a loose cable
momentarily (for a few milliseconds) prevented the
received signal from being digitized (sometimes called
"dropout"). Note the similarity (and differences) to
the motion/instability case. The width of the band at
the center is inversely proportional to the duration
of the dropouts. Interferogram here.
Look closely to see the droputs.
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af1001.sur - (receive freq. = 0)
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af2001.sur - (receive freq. = -3900)
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These two images demonstrate two types of
audio-frequency problems (in this case, at AC
power-line - "mains" - frequency, 60 Hz and
harmonics, especially 300 Hz):
- Modulation of the NMR signal at an audio rate
- Audio signal component at digitizer input
Problem #1 shows up as ghosts, weak copies
of the real image, displaced along the phase-encoding
axis. The number and intensity of the ghosts depends
upon the relationship between the period of the audio
modulation and the repetition time Tr. Note that this
is similar, but not identical, to the general instability case
shown below, where uncorrelated effects cause a
general smearing, rather than discrete ghosts.
Problem #2 shows up as lines or spots at the
appropriate points along the frequency axis. Lines
are generated if there is no correlation between the
audio period and Tr, otherwise, discrete spots occur.
In this case, the frequencies are +/- 300 Hz. Since
the spectral width is 50 KHz and there are 256 points
along the frequency axis, the spots or lines are about
3 pixels apart. Notice that changing the rf reference
frequency by 3900 Hz causes the image to move
(since it is a real radio-frequency signal) but has no
effect on the position of the artifact (since it is
not present at the radio-frequency).
Both problems can be mitigated by use of AC-line
synchronization (line trigger). This results in all
of the intensity in these two columns being collapsed
to the central line of the image. See also the
discussion of the DC
artifact, and the
chemical shift example.
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cs_a001.sur - 12.5 kHz
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cs_b001.sur - 50 kHz
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A cross-section of a raw egg demonstrates the
chemical shift artifact. Both images were
acquired with Te/Tr 400/30, but two different readout
gradients. On the right, a 50kHz bandwidth and 16
averages, on the left, 12.5kHz bandwidth and 1 average
(averaging adjusted to keep signal-to-noise levels
constant). Note the apparent displacement of the yolk
image in the left image. This is because the yolk is
principally fat (see the egg
chemistry discussion). The fat has a chemical
shift ranging from about +100 to -700 Hz relative to
the water of the egg white. 700 Hz for a 12.5 kHz
bandwidth over 256 pixels corresponds to a shift of 14
pixels. The diffuse border of the fat area is due to
the variable chemical shift of the lipids.
The narrow bandwidth image also displays a
particularly severe case of audio frequency
artifacts. These
are spread out over several pixels due to the narrow
bandwidth, and the presence of multiple harmonics of
60 Hz (principally 180 and 300 Hz). The FID artifact is also present in this
image, as a line at the top, showing the use of phase
cycling to avoid corruption of the image itself. The
FID disappears in the wide-bandwidth image due to
signal averaging.
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clip001.sur - Clipping
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The receiver gain was increased (by 20 dB) so that
the signal level was larger than the maximum ADC
(Analog-to-Digital-Converter, or digitizer) value. To
compensate, the reconstructed image brightness was
scaled by x0.1 relative to the others.
This effect is called "clipping" because on a plot
of signal amplitude vs. time, it looks like the top
and bottom of the echo has been "clipped off" with
scissors. Note the overall intensity loss as well as
the extensive signal reconstructed outside the
object. Raw data here.
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dc001.gif - DC Offset
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Actually, if you look carefully, all of the images
in this collection have this artifact - a single pixel
at the exact center which is brighter or darker than
the surroundings. This is the Fourier transform of a
constant offset in the raw data. This is extremely
common, since temperature fluctuations often cause
dc-coupled amplifiers to have non-zero outputs with
zero input. Normally it is compensated for in
software, by applying a "dc correction" or "baseline
correction" before the FT. To produce the example,
the reference data was reprocessed using only 128
phase encodings. Because zero-filling is employed
before the FT, a Gibbs artifact results in the spot
"ringing" into adjacent pixels. See also the Gibbs
example.
Note: do not confuse the two pixels on either side
of center with this DC artifact. These two bright
spots also appear in most of the collection, and
result from an audio (line) frequency artifact (see above) which is
perfectly synchronized with the acquisition, and hence
reconstructs to the center of image space. The three
pixels together make a tiny "hyphen". Note that the
zero-filled (Gibbs) example does not show these
adjacent pixels ringing: this is because their
intensity is much closer to the average image
intensity than the that of the DC spike.
This artifact should not appear in a true "digital"
receiver which has IF digitizing and performs
quadrature detection numerically.
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8bit001.sur - Digitizer quantization
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The original data set was processed (with viewit)
to reduce the precision. Originally digitized at 16
bit resolution (values +32767 to -32768), the lower 8
bits were all set to zero, resulting in an effective
digitizer precision of only 8 bits (+127 to -128). The
noise level is smaller than the digitizer quantum in
this case, so we see the effects of quantization. No
raw data available.
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FID (with spin echo)
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fider001.sur - FID
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A combination of B1 inhomogeneity, poor slice
profile, and insufficient spoiler gradients between
the refocussing pulse and the readout interval of a
spin-echo sequence results in an FID signal
being detected along with the echo. Since the FID is
not phase encoded (normally the phase encoding occurs
before the refocussing pulse), it is not
dispersed along the phase encoding axis, but appears
as a line across the center of the image. This
example is a very mild case. Receiver turn-on
artifacts (not true NMR signals) appear similarly,
except that they extend into the signal-free region,
while the FID (a real NMR signal) is confined to the
projection of the sample along the readout axis.
Proper phase cycling can relegate this artifact to
the edge of the image. This is demonstrated in the chemical shift example.
The FID can be seen at the left edge of the interferogram. The
reference interferogram was acquired with phase
alternation. See if you can see the difference.
FID artifacts cannot occur on gradient echo images,
but receiver turn-on is still possible on gradient
echoes. See shimming for an
example of this.
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gibbs001.sur - Gibbs Artifact
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Only 64 samples were acquired in the phase encode
direction. Also, although 256 samples were acquired in
the readout direction, 192 of them were discarded,
keeping only the central 64 for reconstruction. In
addition to the expected blurring (loss of resolution)
there are low intensity "rings" parallel to the edges
of the sample. Contrast enhanced slightly relative to
other images in this series. Raw data here.
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moire001.sur - Moire
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When echoes from different excitation modes occur
within the acquisition window, but with slightly
different echo times, an interference pattern
occurs. This looks like the pattern of superimposed
screens, known as a Moire' pattern, and can be seen at
the bottom of the image above. The second echo is
often a stimulated echo, or a multiple-quantum
echo. The spacing of the fringes is inversely
proportional to the difference in echo timings. This
artifact is often sensitive to shimming or
suxceptibility gradients.
This image was acquired with a shorter Tr (200msec,
less than T2 for this sample) and with the "spoiler"
or "crusher" gradient at the end of the sequnece
turned off. Receiver gain was increased to compensate
for T1 losses. Contrast considerably enhanced,
emphasizing some B1 inhomogeneity. Sometimes both
echoes can be seen in the interferogram, in this
case the second echo is in the upper right quadrant.
Raw data here.
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motio001.sur - Motion
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shmv001.sur - Instability
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The sample in the left image was jostled with a
stick during the acquisition. Virtually any
instability or fluctuations in the system will
cause artifacts of this type, of greater or lesser
intensity. This includes power supply problems,
mechanical vibrations, cryogen boiling, large iron
objects moving in the fringe field, loose connections
anywhere, or pulse timing variations, as well as
sample motion. The displacement need not be very
much, as can be seen from the absence of any shift
along the frequency axis. Raw data here.
A much more extreme example is shown on the right,
where one of the shim currents was changed drastically
several times during the acquisition. This results in
a frequency shift, as well. This particular case is
much less common, but motion along the frequency axis
can look similar.
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quad001.sur - Quadrature ghost
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The gain of the imaginary receiver channel was
changed slightly, prior to the aquisition. (Phase
errors between the two quadrature channels can also
cause the same effect.) Note that the ghost is
displaced diagonally across the center in both
readout and phase encoding directions, in contrast to
almost all other types of ghosts. Contrast
enhanced. Raw data here.
This artifact should not appear in a true "digital"
receiver which has IF digitizing and performs
quadrature detection numerically.
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rfi001.sur - (50kHz spectral width)
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rfi2001.sur - (100kHz spectral width)
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The interfering signal is at 170.000000 MHz, while
the center frequency of the images is at 170.029470
MHz. The left image has a 50 kHz spectral width. The
interference is thus 4470 Hz beyond the left
(low-frequency) edge of the image, and is attenuated
and aliased to the high frequency side. The right
image has a 100 kHz spectral width. This artifact is
thus within the receiver bandwidth, and is much
stronger. In the second image, the interference is
strong enough to be visible as a horizontal
herringbone pattern in the interferogram. Raw data
here.
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noise001.sur - Random Noise
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There are various noise sources in any electronic
system, including Johnson noise, shot noise, thermal
noise, etc. These are more or less indistinguishable
in images. For this image, the slice thickness was
reduced by a factor of 10 (to 1mm) to reduce the
signal 10-fold. The receiver gain was increased by a
factor of 10 (20dB) to bring the signal back to the
original level. The noise is now 10 times as
intense.
This appearance is often described as "grainy",
"snowy", or "noisy", or "low SNR" (Signal to Noise
Ratio). Note that it is essentially patternless. The
other artifacts shown here are NOT, and should not be
referred to as "noise". Raw data here.
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rfhom001.sur - RF inhomogeneity
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A 2-inch square piece of copper foil was placed at
the left side of the phantom to intercept the B1
field. The shadowing (due to RF eddy currents in the
copper foil) results in almost complete signal
dropout. No change in the apparent pulse calibration
was observed. Similar effects - uneven illumination -
occur with some types of RF coils, particularly, but
not limited to, surface coils .
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shim1001.sur - Spin Echo
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shimdiff.gif - (Reference Subtracted)
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shim2001.sur - Gradient Echo
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The effect of mis-set shim currents (i.e. Bo
inhomogeneity) depends on the imaging technique.
These two examples were acquired with the ZXY shim
current misadjusted. The left image above was acquired
with the spin-echo sequence used for most of the rest
of the gallery, and a 1.86 A ZXY error. The only sign
of the shim problem is a tiny geometric distortion -
less than 2 pixels (viewed along the Z axis). The
extent of the distortion depends on the readout
gradient strength, of course. The center image shows
the difference between the distorted and the reference
image.
The right image was acquired with a gradient echo
sequence, using similar excitation parameters, but
only one third of the current error (0.61 A). The Z
(slice) component of the shim error now causes a
tremendous signal loss (failure to refocus) in areas
where it is large.
Note the presence of receiver turn-on
artifact in the gradient echo image (see also: FID artifact).
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adcer001.sur - Stuck ADC Bit
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Once again, viewit
has been used to modify the data, by performing a
bitwise OR with a binary value having one bit set to
zero (e.g. 1111011111). This artifact is uncommon
with modern hardware, but not impossible. It can
occur if there are bad memory locations or bad
connectors in the parallel data bus. Notice the
similarity to the
Digitizer
Quantization example. The
severity depends on which bit is stuck.
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susc001.sur - Susceptibility Distortion
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A US quarter-dollar coin (1992) was placed next to
the phantom. The metallic object is too small, or too
poorly conductive, to cause significant RF
inhomogeneity (compare with the real thing, above). But it does
distort the magnetic field, in a manner similar to,
but more severe than, a shimming
error. Careful inspection reveals a small
distortion of the circular phantom profile at the left
side. A characteristic feature of this type of
distortion is the accompanying bright-spot/dark-spot
effect. In this case, the edge of the phantom near
left center is a bit darker, and there is a brighter
area just below it. This differs from the RF
inhomogeneity effect in that signal appears to be
"conserved". The effect is subtle in this image
because the coin is distant from the signal volume.
Closer contact can produce much more severe
effects.
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All data were acquired on the Beckman MRI system,
using the SMIS volume RF coil.
Unless noted, the object is a phantom consisting of
a 4oz (125ml) Nalgene plastic bottle with 5mM CuSO4
in water. T1 ~ 300 msec, T2 ~ 270 msec.
Unless noted, all images are acquired with a very
conventional 2D spin echo spin-warp imaging
scheme.
Unless noted, data were processed using a simple
two-dimensional Fourier transform (without
time-domain weighting), and are presented as the
magnitude of the signal, scaled by a fixed factor of
0.01.
The parameters for the standard (Reference) image
follow:
(from rfi.mrd)
C:\BMRL\SEQLIB\SE2D.PPL
OBSERVE_FREQUENCY 170.029470 MHz
rec_freq, 0
tr, 400 msec
te, 20 msec
sample_period, 20.0 µsec (50 kHz spectral width)
no_samples, 256
no_views, 256
no_averages, 1
view_block, 1
slice_block, 1
phase_cycle, 1
orientation, 1
gr_var, -512
gp_init_var, -512
:FOV 75.0003
slice_off_freq, 0
:SLICE_THICKNESS gs_var, -128, 10
:SLICE_SEPARATION slice_offset, 150, 1
:NO_SLICES no_slices, 1
:SLICE_INTERLEAVE slice_interleave, 1
flip_angle, 90
obs_power, 4
gr_comp_scale, 0
gs_comp_scale, 0
tc1, 1000
tc2, 5000
g_spoil, 820
triggered, 1
no_dummy_scans, 0
:DISCARD no_discard, 2
:DATA_TYPE 0x13
:_ObserveTransmitGain -33
:_ObserveReceiverGain 250
:_ObserveReceiverAttenuation -170
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C.D.Gregory: April 1, 1997
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